Moreover, we also performed separate meta-analyses for BRCA1 and BRCA2 mutation carriers since we believe that pooling of BRCA1 and BRCA2 mutation carriers for analyses of AIB1 poly-Q repeat polymorphism could be disputable considering the substantial differences in effects of AIB1 polymorphism in these groups and also assuming the diverse histopathological and molecular characteristic of breast tumors in BRCA1 and BRCA2 carriers. The gene discussed is NCOA3; the disease is breast neoplasm.