Angiogenesis is also a key pathological marker in neuroblastoma (Katzenstein et al., 2000; Ribatti et al., 2004) and many works correlate its induction to the amplification and/or overexpression of MYCN transcription factor (Ribatti et al., 2002; Kang et al., 2008). The gene discussed is MYCN; the disease is neuroblastoma.