SST controls cancer cell proliferation via the interference with different signaling pathways (PTPs, JAK2, Ras/ERK, and Pi3K/Akt) resulting in cytostatic effects mediated by the induction of involving the induction of cell cycle inhibitors p27 or p21, or tumor suppressors, like Zac1 [33, 109–112]. The gene discussed is SST; the disease is cancer.