CORT and neoplasm: The role of specific SST receptor subtypes in SST antiproliferative effects have been identified, since sst1, 2, 4, and 5 are mainly involved in the arrest of cell cycle progression, while sst2 and 3 are also able to activate proapoptotic pathways, as well as anti-angiogenic signals, an indirect control of tumor growth [44, 45].