Kidney tissue mononuclear cell infiltration score (Figure 4), alveolar macrophage count (Figure 5), histologic kidney injury score (Figure 6), histologic lung injury score (Figure 7), kidney tissue immunreactivity (caspase 3) score (Figure 8), and lung tissue immunreactivity (M30) score (Figure 9) in the sepsis group were significantly increased compared with the sham and sepsis + dex groups (P < 0.05). Here, CASP3 is linked to Sepsis.