Here we report that mTOR signaling in K7M2 cells is associated with higher aldehyde dehydrogenase (ALDH, a cancer stem cell marker) activity, increased resistance to oxidative stress, increased proliferation, migration, and invasion, and higher bone morphogenetic protein (BMP2) and vascular endothelial growth factor (VEGF) expression than in the less metastatic K12 cells. This evidence concerns the gene MTOR and cancer.