P2RY12 and Increased total eosinophil count: Mice lacking the classical cysLT receptors maintained LTE4-induced eosinophilia, goblet cell metaplasia and IL-13 expression in response to low-dose of aerosolized allergen but P2Y12 knock-out and platelet-depleted mice (a cell type highly expressing P2Y12) showed a substantial loss in those functions.