The high APE1 expression (score 2 and 3) and low expression (score 0 and 1) in NSCLC tissues were shown no significant difference among age, gender, smoking status, histological type and TMN stages (p>0.05, chi-square test, shown in Table S2), which were the same as the previously reviews [24], [31]. Here, APEX1 is linked to non-small cell lung carcinoma.