Fabry disease (FD, OMIM # 301500) is an X-linked lysosomal storage disorder caused by mutations in the gene (GLA; Gene/Locus MIM # 300644, Ref Seq NM_000169.2) that encodes the lysosomal hydrolase α-galactosidase A (α-Gal A, EC 3.2.1.22) [1]. The gene discussed is GLA; the disease is Fabry disease.