CDK4 and glioblastoma: Some of these alterations, such as del (1p36), del (2p21), +7, del (6q27q29)/−6, EGFR (7p11.2), MDM2 (12q15) and CDK4 (12q14.3) amplification, −10, amplification of 15q24.1, del (17p13)/−17, −19, −22 were known to be associated with glioblastomas [14], [15].