Further, we took advantage of EBV-LMP1 with its many known intracellular signaling pathways to explore the mechanistic link between EBV-LMP1 and TPST-1, and studied how the induction of TPST-1 by LMP1 might contribute to the highly metastatic character of NPC. Here, TPST1 is linked to nasopharyngeal carcinoma.