In turn, 2 T-cell lymphoma samples could be easily distinguished from both pediatric solid tumors and B-cell lymphomas with the screening panel (panel 1 in Table S2) based on their CD45+lo, SmCD3+lo and CyCD3+ phenotype; in addition, these cells also showed a CD4+, CD8−, CD1a+, CD99+, CD2+, CD5+, CD27+, CD71+ and CD81+ phenotypic profile, lacking CD7−, CD117− and B-cell markers once the appropriate screening and characterization panels (panels 1 and 4 in Table S2, respectively) were used. The gene discussed is CD81; the disease is B-cell non-Hodgkin lymphoma.