Immunofluorescence showed that VCAM-1 was not expressed under basal conditions but was upregulated and clearly localised to glomeruli in mice with myocardial infarction (Fig. 3a) and to the same cells expressing PECAM-1, indicating upregulation by glomerular endothelial cells (Fig. 3c). This evidence concerns the gene PECAM1 and myocardial infarction.