OCC is a chemo-resistant tumor with a relatively poor prognosis [5], and recent reports suggest that specific molecular events such as an activating mutation of the alpha-catalytic domain of PI3 kinase (PI3K) [6] or an inactivating mutation of AT-rich interactive domain 1A (ARID1A) [7], [8] may play roles in the tumorigenesis of OCC. This evidence concerns the gene ARID1A and neoplasm.