Moreover, detection of filopodia by Phalloïdin detection showed that on laminin, CD44 overexpression increased filopodia numbers per cell (Fig. 3C) and filipodia length (Fig. 3D) compared to controls, suggesting that CD44 overexpression may facilitate NPC invasiveness on extracellular matrix components. The gene discussed is CD44; the disease is nasopharyngeal carcinoma.