TRPV1 and colonic neoplasm: Western blot analysis showed that when kidney cells (HEK-293e found to express TRPV1), alveolar epithelial cells (MLE-12), carcinoma breast cancer cell line (MCF-7) or colon cancer cells (HT-29) are treated with the TRPV1 agonist capsaicin, they accumulate Hsp70, Hsp90 and Hsp27 proteins (Fig. 1).