The same authors demonstrated that Mecp2 null mice develop non fatty acid liver storage disease (NAFLD), which is likely due to the link between Mecp2 and histone deacetylase-3 (Hdac-3, OMIM*605166) (Communication by Ebert D, at 7th World Congress on Rett Syndrome, New Orleans, 2012). Here, MECP2 is linked to metabolic dysfunction-associated steatotic liver disease.