We first showed that transcript levels of miR-3148 and TLR7 were inversely correlated in PBMCs from 16 patients with SLE and 21 healthy controls (R2 = 0.255, P = 0.001; Figure 3B), suggesting the possible regulation of TLR7 expression by miR-3148. This evidence concerns the gene TLR7 and systemic lupus erythematosus.