Recently, advanced genetic methods involving targeted exome capture, next generation DNA sequencing, and bioinformatics computer analyses implicated FAM20A (family with sequence similarity 20, member A) located on chromosome 17q24.2 as the defective gene in a recessive disorder manifesting the same oral features as described above [22], [24] and designated “Amelogenesis Imperfecta and Gingival Fibromatosis Syndrome” (AIGFS; OMIM #614253). The gene discussed is FAM20A; the disease is amelogenesis imperfecta type 1G.