ESR1 and breast cancer: For example, most of the genes used for the Oncotype DX breast cancer recurrence score directly converge to one of our identified attractors: MMP11 to the mesenchymal transition attractor; MKI67 (aka Ki-67), AURKA (aka STK15), BIRC5 (aka Survivin), CCNB1, and MYBL2 to the mitotic CIN attractor; CD68 to the lymphocyte-specific attractor; ERBB2 and GRB7 to the HER2 amplicon attractor; and ESR1, SCUBE2, PGR to the estrogen receptor attractor.