LY75 and pulmonary tuberculosis: It is expressed by DCs and thymic epithelial cells.9,10 In human tissue, immunohistochemistry CD205 has been used to identify DCs in the tonsils11 and spleen.12 CD205 expression is up-regulated upon maturation of human monocyte-derived dendritic cells.13 Alveolar macrophages in mouse and human lung tuberculosis tissues also express CD205.14,15 CD205 is also expressed by activated human plasmacytoid DCs, another component of major subsets of DCs (i.e. the other component of mouse and human DCs is myeloid DCs [also known as conventional DCs and classical DCs]).16