We also tested the action of normal-IgG or BFA-IgG (10−8 M) (n = 3), and we did not observe any effect on VEGF-A expression either in the supernatants or in the lysates obtained from tumor cells in comparison to control (MCF-7 cells without treatment, considered as 1) (Fig. 3A and B). The gene discussed is VEGFA; the disease is neoplasm.