TNFRSF10B and neoplasm: Multivariate analysis, including variables associated with overall survival in the univariate analyses with p<0.2, (i.e. gender, grading, median tumor size, and TRAIL-R2 membrane staining) confirmed the independent prognostic significance of membrane staining for TRAIL-R2 in this subgroup (adjusted for all: HR 0.47 [0.23–0.96], p = 0.041; backward elimination: HR 0.44 [0.22−0.87], p = 0.019).