STAT3 and familial dilated cardiomyopathy: To assess whether STAT3 inhibition could also act therapeutically by preventing the progression of autoimmune myocarditis to DCM, known to occur after day 21 and to peak at day 42 (Cihakova & Rose, 2008), EAM was induced in BALB/c mice followed by administration of the SF-1-066 inhibitor starting at day 21 post-immunization.