It has been well established for over two decades that HIV-1 infection is branded with loss of T-cell proliferation accompanied with limited IL-2 production (Lane et al., 1985; Shearer et al., 1986; Miedema et al., 1988; Clerici et al., 1989; Gruters et al., 1990; Fan et al., 1993). Here, IL2 is linked to HIV-1 infection.