Our study was motivated by the fact that prior studies have shown that the ATP1A2 gene is implicated in rare forms of migraine (familial hemiplegic migraine type II) which has features typical of migraine with aura in addition to features consistent with transient brain ischemia (Hansen et al. 2011; Mourand et al. 2012; Eikermann-Haerter et al. 2012). This evidence concerns the gene ATP1A2 and migraine disorder.