In particular, 3-indolyl-5-phenylpyridine showed antiproliferative activity in the range 5–15 μM and inhibited CDK1 at 0.3–0.7 μM level [31]; phenylthiazolyl-7-azaindoles showed antiproliferative activity against a wide range of human tumor cell lines at micromolar to nanomolar concentrations and inhibited CDK1 with IC50 values in the range 0.41–0.85 μM [32]. This evidence concerns the gene CDK1 and neoplasm.