Neutrophil gelatinase associated lipocalin (NGAL aka lipocalin-2 or siderocalin) has been shown to play diverse roles, from stabilizing matrix matalloproteinase (MMP-9) to combating bacterial infection by binding bacterial siderophores and preventing bacterial iron sequestration to roles in cancer invasion, EMT, and metastasis [187]. The gene discussed is LCN2; the disease is bacterial infectious disease.