Examples of recently described lncRNAs displaying a clear relationship with cancer include HOX antisense intergenic RNA (HOTAIR), metastasis associated lung adenocarcinoma transcript 1 (MALAT1), prostate cancer gene 3 (PCA3), several other oncogenic and tumor-suppressor lncRNAs, as well as transcribed-ultraconserved regions (UCRs). The gene discussed is PCA3; the disease is cancer.