Arf6 expression was suppressed in A2780 ovarian carcinoma cells and A375-SM malignant melanoma cells, which both use α5β1, αVβ3, and syndecan-4 to engage fibronectin, and in both cell lines Arf6 inhibition blocked recycling of α5β1 but not αVβ3 (Figures S5B, S5C, S5I, and S5J). This evidence concerns the gene ARF6 and ovarian carcinoma.