LGALS3 and Insulin resistance: Calculation of the homeostatic model assessment index for insulin resistance (HOMA-IR) indicated the presence of insulin resistance in both DIO WT and Gal-3 KO mice compared to their respective Lean groups, with a non-significant elevation of the index in DIO Gal-3 KO versus DIO WT mice (the HOMA2 index was 3.1+/−0.3, 3.1+/−0.2, 5.7+/−0.5 and 8.5+/−1.3 in Lean WT, Lean Gal-3 KO, DIO WT and DIO Gal-3 KO mice, respectively.