To this purpose, we evaluated by quantitative immunofluorescence the percentage of ICAM1 positive cells in HPMC monolayers after the first confluence: consistent with the increased senescent state, the HPMCs from colon cancer patient (#062), which appeared also to better contribute to the adhesion of the cancer cells in the experiments previously described (Fig. 4), showed an higher percentage of ICAM1 positive cells respect to the other mesothelial cells (Fig. 5C). Here, ICAM1 is linked to colonic neoplasm.