To overcome this limitation, we created an allelic series of RERE-deficient mice using the om allele and a novel hypomorphic Rere allele, eyes3 (c.578T>C, p.Val193Ala; MGI: 3577417), which we identified in an ENU-based screen for autosomal recessive phenotypes based on the presence of microphthalmia [21]. This evidence concerns the gene RERE and microphthalmia.