In a large retrospective cohort study, it has been reported that the prevalence of ALT elevations (i.e. defined as serum ALT >40 U/L), as surrogate markers of NAFLD, among a routine clinical care population with AF was high (i.e. 27.6%), although the incidence of new persistent and significant ALT elevations was uncommon [21]. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.