In this regard, an important CT-X antigen, melanoma associated antigen (MAGE) family demonstrated marked variations in expression of MAGE-A1, [6% (4 of 67)], MAGE-A2 [19% (13 of 67)], MAGE-A3 [10% (7 of 67)], MAGE-A4 [13% (9 of 67)], MAGE-A6 [15% (10 of 67)], and MAGE-A12 [9% (6 of 67)] in invasive breast cancer patients [28]. This evidence concerns the gene MAGEA3 and invasive breast carcinoma.