Several genes that exert their effect through relatively common allelic variants have been shown to be associated with SLE by GWA studies [9], [10], [36]–[41] One of most prominent susceptibility factors for SLE was found to be a SNP (rs1143679) which confers the R77H amino acid substitution in CD11b. This evidence concerns the gene ITGAM and systemic lupus erythematosus.