Individuals with a greater number of suspected AFB-related high-risk genotypes (GSTM1-null, mEH-YH/HH, XRCC1-AG/GG) faced a greater risk of HCC than those without any high-risk genotypes, especially among individuals with higher AFB exposure [13], [17]–[19]. This evidence concerns the gene XRCC1 and hepatocellular carcinoma.