Furthermore, the MDM2 SNP309 polymorphism was associated with a significantly increased risk of gastric cancer in recessive model (GG versus GT/TT, OR = 1.49, 95%CI = 1.30–1.72), but not in dominant model (GG/GT versus TT, OR = 1.18, 95%CI = 0.84–1.65). This evidence concerns the gene MDM2 and gastric cancer.