SUZ12 and posterior cortical atrophy: In our study, SUZ12 was significantly down-regulated after DHT stimulation, and identified as a novel target of miR-19a, it is possible that PCa’s epigenetic maintenance may be partly influenced by miR-19a through down-regulating SUZ12, and then to release SUZ12 target gene expressions which possibly contribute to PCa aggression and poor prognosis.