LEP and androgen insensitivity syndrome: Leptin and bone mineral density. In Hong Kong, China, Tam et al.[80,81] in AIS and control girls, evaluated correlations between each of leptin and soluble leptin receptor (sOB-R) and volumetric bone mineral densities (vBMDs) of various bone compartments scanned at the distal radius using high resolution peripheral quantitative computed tomography (HR- pQCT).