In addition, the reinforcement of mTOR signaling in medulloblastoma CSCs may contribute to radioresistance of these cells, and contrarily, mTOR inhibition could increase radiosensitivity [115]; (2) Fibroblast growth factors (FGFs), which comprise a large family of signaling molecules with various functions in development as well as in adult [116]. The gene discussed is MTOR; the disease is medulloblastoma.