These genes were selected through the evaluation of the literature for genes implicated in cancer metastatic prognosis, specifically the epithelial to mesenchymal transition or EMT phase, and experiments that explored potential Grhl2-associations in terms of both mRNA and protein expression (Table S2), using murine and human breast adenocarcinoma cell lines (4T1 and MCF-7), as well as, a human breast epithelial cell line (MCF10A). The gene discussed is GRHL2; the disease is breast adenocarcinoma.