GPT and acute respiratory distress syndrome: Both serum ALT activity (Fig. 5B) on day 14 and AP activity (Fig. 5C) on both days 9 and 14 post-inoculation were significantly increased over saline (control) levels in reovirus 1/L-ALI/ARDS mice that was reduced to control levels in curcumin-treated, reovirus 1/L-ALI/ARDS mice.