Interestingly, an early significant increase in the expression of IL-6, G/M-CSF and MCP-1 was observed on day 5 in curcumin-treated reovirus 1/L-ALI/ARDS as compared to untreated reovirus 1/L-ALI/ARDS mice or saline (control) mice (Fig. 7A). The gene discussed is CCL2; the disease is acute respiratory distress syndrome.