Two multivariate analysis were performed (Table 4): the first including only preoperative variables identified age, AFP >400 μg/l and albumin ≤37 g/l as significant predictors; the second including both pre- and the postoperative variables identified diabetes, AFP >400 μg/l and albumin ≤37 g/l as preoperative independent predictors of survival, while postoperative ascites and the opportunity to undergo liver transplantation (Figure 4) were the sole postoperative predictors. The gene discussed is AFP; the disease is diabetes mellitus.