After the above adjustments, the associations were increased between GSTT1 and GSTM1-GSTT1 polymorphisms and HCC risk (ORGSTT1 = 1.45, 95% CI: 1.24 to 1.69; ORGSTM1-GSTT1 = 1.98, 95% CI: 1.43 to 2.74). The gene discussed is GSTM1; the disease is hepatocellular carcinoma.