Although FoxA2 is described as a downstream target of C/EBPα in the fetal lung and in vitro[7], [50], FoxA2 was strongly expressed in the urethane-induced tumors of CebpαΔ/Δ mice (Figure S3A) and Foxa2 mRNA was also induced in the tumors from CebpαΔ/Δ mice (Figure S3B), suggesting that FoxA2 does not suppress urethane-injected tumor in CebpαΔ/Δ mice and is not a downstream target of C/EBPα in adult mice. Here, FOXA2 is linked to neoplasm.