Previously, we found that Aur-A promoted epithelial–mesenchymal transition and invasion in nasopharyngeal carcinoma (NPC) mediated by mitogen-activated protein kinase (MAPK) phosphorylation [31], and increased LSCC cell growth and migration mediated by activation of Akt1 [20]. Here, WNK2 is linked to nasopharyngeal carcinoma.