After conducting a multivariate logistic analysis, the number of GT repeats (Odds ratio: 0.94 per GT repeat, 95% CI 0.90–0.99, p = 0.01) and LAD (Odds ratio: 1.08, 95% CI 1.02–1.15, p = 0.01) remained independently associated with AF recurrence when adjusted for age, sex, hyperlipidemia, statins, angiotensin converting enzyme inhibitor/angiotensin receptor blocker, and the incidence of non-paroxysmal AF. The gene discussed is ACE; the disease is hyperlipidemia.