Interestingly, we observed that ectopic expression of GFP-tagged ABCD2 resulted in a decrease in the ratio of C26∶0/C22∶0, indicating that accumulated VLCFA levels were reduced in the fibroblast cells from an X-ALD patient by ectopic ABCD2 (Fig. 5C). Here, ABCD2 is linked to X-linked adrenoleukodystrophy.