FLT4 and neoplasm: Based on an extensive review of the literature and detailed analysis (including northern, FACS, western blotting, RT-PCR, immunoprecipitation and immunohistochemistry) of 62 tumor cell lines and staining of 456 tumor tissues (including 35 histological types), one group reported that expression of VEGF-R3 is negligible in most solid tumor cells when compared to vascular and lymphatic endothelial cells.