All mice injected with either control Panc-1 cells (5/5) or Bmi1 silenced Panc-1 cells (5/5) showed tumor formation in the pancreas, however Bmi1 silenced Panc-1 cells formed tumors that were 2.5 times smaller on average than tumors derived from control Bmi1 expressing Panc-1 cells (1.21±0.23 cm3 vs. 0.42±0.09 cm3, *p<0.05, Figure 4A, bottom panel). This evidence concerns the gene BMI1 and neoplasm.