Tissue sections from 10 different primary human pancreatic adenocarcinomas, 10 normal pancreas samples, and 16 preneoplastic PanIN lesions with varying degrees of epithelial dysplasia (PanIN 1 to PanIN3) were examined for Bmi1 expression following immunohistochemical staining. This evidence concerns the gene BMI1 and pancreatic adenocarcinoma.